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Reference SA/BGU
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Level Collection
Extent 65 boxes
Extent 1 o/s folder
Title Medical Research Council Blood Group Unit (1935-1995)
Date 1927-1993
Name MRC Blood Group Unit (1935-1995)
Description

The records cover the period 1927-1993, although the majority date from the 1940s to the 1970s. Notable series include general correspondence with colleagues world-wide, 1935-1984; Dr Race's research papers on human genetic markers, late 1930s/early 1940s; files of correspondence, research notes, pedigrees etc. on blood grouping investigations, 1942-1993; and a comprehensive collection of photographs recording BGU staff at work and play, 1927-[1980s].

Arrangement

By section as follows:

A. Galton Lecture 1937;

B. Race and Sanger Papers;

C. Rh Notation;

D. BGU Laboratory Procedures;

E. General Correspondence;

F. Blood Group Investigations (Rh and LW; Moores; Xg and 12E7 [CD99]; MN; ABO(H); P; Lu; Colton; Di; Do; Duffy; Ge; HDN; Kell; Kidd; Lewis; Rd; Yt; Private/Ana; Chimeras and Mosaics; Monosomy-7);

G. Linkage;

H. Pedigrees;

J. Lectures and Meetings;

K. Publications;

L. Photographs

Historical Background

The MRC Blood Group Unit succeeded the Galton Laboratory Serum Unit set up in 1935 under the direction of Professor (later Sir) Ronald Fisher and financed through the Medical Research Council by the Rockefeller Foundation. The Serum Unit was based at University College, London, and re-located to Cambridge during the Second World War. In 1946, the Unit was reconstituted at the Lister Institute for Preventive Medicine as the Blood Group Research Unit, under the directorship of Dr Robert Race.

The need for safe transfusion therapy intensified blood group research in the run-up to the Second World War, and in 1940 Landsteiner and Wiener discovered the Rh factor, building on foundations laid by Levine and Stetson in 1939. From 1946 the MRC Blood Group Unit acquired an international reputation in the highly specialised field of haematology, extending its work in 1965 into the genetics of blood groups. Upon the retirement of Dr Race in 1973, Dr Ruth Sanger became director of the Unit. Under Dr Sanger's direction, the Unit continued to make a unique contribution to the identification of blood groups, and to the applications of the blood group systems to the problems of human genetics. In 1983, upon the retirement of Dr Sanger, Dr Patricia Tippett became director. The MRC Blood Group Unit moved from the Lister Institute to premises at University College, London in 1975. It was disbanded in September 1995, although its work continues in other research centres.

Acquisition Details These records were given to the Contemporary Medical Archives Centre (known as Archives and Manuscripts following its merger with Western Manuscripts in July 2000) by Dr Patricia Tippett of the Medical Research Council (MRC) Blood Group Unit in April 1996 (Acc No 628) and March 1998 (Acc No 753), and by the Medical Research Council in May 1996 (Acc No 635).
Accession Number 628
Accession Number 635
Accession Number 753
Access Status Certain restrictions apply
Access Conditions

The majority of the papers are available subject to the usual conditions of access to Archives and Manuscripts material, by prior appointment with the Archivist after the completion of a Reader's Undertaking.

Please note that file SA/BGU/F.1/39/3 is closed until January 2056, and SA/BGU/F.20/1 is closed until January 2042.

Access to the following files is restricted as they contain sensitive personal data, and readers can only have access after applying to the Archives department and completing a Restricted Access undertaking form:

SA/BGU/E.14/2

SA/BGU/F.2/6

SA/BGU/F.3/2/1

SA/BGU/F.3/13/1

SA/BGU/F.3/22/1

SA/BGU/F.6/1/2

SA/BGU/F.18/1/2

SA/BGU/F.20/3

SA/BGU/F.20/10

SA/BGU/G.3/2

SA/BGU/H.2

Reproduction Conditions Images are supplied for private research only at the Archivist's discretion. Please note that material may be unsuitable for copying on conservation grounds. Researchers who wish to publish material must seek copyright permission from the copyright owner.
Copies The following copy photographs are held by Wellcome Images:
SA/BGU/F20/1, Blood pedigree of Mrs. Mackenzie and her family, taken from a letter from Robert race to Alan Drury, 3rd May 1935, L0046124
SA/BGU/F20/1, Photograph of fused chorions of unicornual bovine twins, L0046125
SA/BGU/F20/1, Diagram of a blood pedigree dated 28th April 1953 where Mrs. Mackenzie is divided into I and II, L0046123
Related Material

In the Wellcome Library:

Papers of AE Mourant (1904-1994) relating to his work in the Blood Group Reference Laboratory etc. (PP/AEM);

records on the arrangement of and publicity for the Blood Transfusion Service, 1943-1949 (GC/107);

the papers of Dame Janet Vaughan (1899-1993) on work with the Emergency Blood Transfusion Service, 1939 (GC/186);

records of transfusions by the British Red Cross Society Blood Transfusion Service, 1929-1936 (GC/261);

papers relating to blood transfusion during World War II in the Royal Army Medical Corps "Muniments Collection" (RAMC).

See also Sources Leaflet no 52 "Blood".

Material held elsewhere:

The National Archives, Ruskin Avenue, Kew, Richmond, Surrey TW9 4DU hold 70 files of correspondence, papers, reports and lecture notes for the Medical Research Council Blood Group Unit, 1936-1994 (PRO reference FD 8).

Relevant Publications R R Race and R Sanger, Blood Groups in Man (Blackwell Scientific Publications, 6th ed, 1975)
Notes

Abbreviations:

AGM Annual General Meeting

BGU Blood Group Unit

BMJ British Medical Journal

(c) colour

CMAC Contemporary Medical Archives Centre

MRC Medical Research Council

n.d. not dated

UCL University College London

Subject Blood transfusion
Subject Genetics
Subject Hematology
Subject Research Support
Subject Women in medicine
Subject Blood
MaterialType Archives - Non-digital
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